Protein Purification
Abcam x AV939, Tankyrase inhibitor, 5MG
MW 312.31 g/mol, Purity >98%. Potent tankyrase (TNKS) inhibitor. Inhibitor of Wnt/β-catenin signaling. (IC₅₀ values are 11 and 4 nM for TNKS1 and 2, respectively). Inhibits TNKS PARP activity. Selectivity over other PARP enzymes and CRE, NK-κB and TGF-β.
The product is subject to the following: Abcam Restricted Use Statement
Biolegend MojoSort™ Human Hematopoietic Progenitor Cell Isolation Kit
MojoSort™ Human Hematopoietic Progenitor Cell Isolation Kit Reactivity: Human; Apps: Cell Sep - Neg; Size: 20 tests
Biolegend MojoSort™ Human Pan B Cell Isolation Kit
MojoSort™ Human Pan B Cell Isolation Kit Reactivity: Human; Apps: Cell Sep - Neg; Size: 20 tests
CPC Scientific H-Ile-Thr-Ser-Phe-Glu-Glu-Ala-Lys-Gly-Leu-Asp-Arg-Ile-Asn-Glu-Arg-Met-Pro-Pro-Arg-Arg-Asp-Ala-Met-Pro-OH (trifluoroacetate salt) 1MG
Amino acid sequence of this peptide that is identical with the C-terminal region of the calmodulin-bing domain. It inhibits Mn2+-stimulated calcineurin activity (IC50 = 10 m M) using [32P] myosin light chain as a substrate but has no effect on Ni2+ -stimulated activity. ONE-LETTER SEQUENCE: ITSFEEAKGLDRINERMPPRRDAMPMOLECULAR FORMULA: C124H205N39O39S2MOLECULAR WEIGHT:2930.34STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [148067-21-4], RESEARCH AREA: Protein Kinases and PhosphatasesREFERENCES: Y. Hashimoto et al., J. Biol. Chem., 265, 1924 (1990)
New England Biolabs, Inc. Chitin Resin – 20 ml
An affinity matrix for the isolation of target proteins fused to an intein-chitin binding domain fusion
Abcam Cilostamide, PDE3 inhibitor, 50MG
MW 342.4 Da, Purity >98%. Potent, selective PDE3 inhibitor (IC₅₀ values are 27 and 50 nM for PDE3A and PDE3B, respectively). Inhibits ADP-induced platelet aggregation (IC₅₀ = 16.8 μM). Antithrombotic effects in vivo. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Hampton Research HR3-180/MRC Maxi 48-Well Crystallization Plate (Swissci) - 40 plate case
HR3-180/MRC Maxi 48-Well Crystallization Plate (Swissci) - 40 plate case. Please note items from this supplier are non-returnable.
Sigma Aldrich Fine Chemicals Biosciences Lipopolysaccharides from Escherichia coli O111:B4 purified by ion-exchange chromatography, TLR ligand tested, MFCD00164401
Lipopolysaccharides from Escherichia coli O111:B4 purified by ion-exchange chromatography, TLR ligand tested
Gold Biotechnology Inc Nickel Agarose Beads (High Density) 50 mL
Nickel Agarose Resin is available in bulk or in prepacked columns. It has a binding capacity of >25 mg/ml with approximately 60 kDa protein. In addition, it allows for purification of proteins under native or denaturing conditions. GoldBio Nickel Agarose works very well with the His-Tag Buffer Set.
Abcam ML130, NOD1 inhibitor, 25MG
MW 287.34 Da, Purity >97%. Potent, selective NOD1 inhibitor (IC₅₀ = 560 nM). Inhibits NOD1-induced NF-κB activation in vitro. Cell-permeable.
The product is subject to the following: Abcam Restricted Use Statement
Abcam ZM 336372, c-Raf inhibitor, 10MG
MW 389.4 Da, Purity >98%. Potent, cell-permeable and selective c-Raf inhibitor (IC₅₀ = 70 nM). Displays 10-fold selectivity over b-Raf. Inhibits carcinoid cell growth. Also inhibits growth and apoptosis in pancreatic cancer cells.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical IRAK4 InhIbItr 1 25mg
An IRAK4 inhibitor (IC50 = 7 nM); reduces resiquimod-induced increases in TNF-α levels in isolated human PBMCs (EC50 = 300 nM)